Mycobacterium

Mycobacterium is a genus within the order Actinomycetales that comprises a large number of well characterised species, several of which are associated with human and animal disease such as tuberculosis and leprosy.

Data Downloads

• FTP site

• BLAST server

The Wellcome Trust and DEFRA has funded the Sanger Instiute to sequence reference genomes for Mycobacterium africanum

Mycobacterium bovis strains AF2122/97 and BCG Pasteur

Mycobacterium canetti

Mycobacterium leprae

Mycobacterium marinum

Mycobacterium microti

Mycobacterium tuberculosis

In collaboration with

Dr. Bouke de Jong, Bacterial Diseases Programme, MRC Laboratories, The Gambia

Prof. Stewart Cole, Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland

Dr. Glyn Hewinson, Veterinary Laboratories Agency, UK.

Dr. Roland Brosch, Unit de Genetique Moleculaire Bacterienne, Institut Pasteur.

Dr. Lalita Ramakrishnan, University of Washington, Seattle, USA.

Dr. John Davies, Department of Microbiology, Monash University, Australia.

Dr. Pamela Small, Department of Microbiology, University of Tennessee, Knoxville, USA.

Dr. Paul Johnson, Department of Infections Diseases, Monash Medical Centre, Australia.

The Sanger Institute has also initiated a Wellcome Trust funded genomics program to look at various aspect of mycobacterial evolution and epidemiology in collaboration with Douglas Young and Sebastian Gagneux, MRC National Institute for Medical Research, Division of Mycobacterial Research, London, UK.

Francis Drobniewski, Barts and The London School of Medicine and Dentistry, London, UK.

Mike Prentice, Department of Microbiology, University College Cork, Cork, Ireland.

Dick van Soolingen, National Mycobacteria Reference Laboratory, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.

Sandra Newton, Imperial College, London, UK.

Derrick Crook, Oxford University, Oxford, UK.

Helen Donoghue, UCL School of Life and Medical Sciences, London, UK.

Noel Smith, Centre for the Study of Evolution, University of Sussex, Brighton, UK.

Dr. Glyn Hewinson, Veterinary Laboratories Agency, UK.

Dr. Roland Brosch, Unit de Genetique Moleculaire Bacterienne, Institut Pasteur.

Published Genome Data

The following genomes are available from EMBL/GenBank with their respective accession numbers

Mycobacterium africanum GM041182 - FR878060

Mycobacterium bovis BCG Pasteur 1173P2 - AM408590

Mycobacterium bovis subsp. bovis AF2122/97 - BX248333

Mycobacterium canetti CIPT 140010059 - HE572590

Mycobacterium leprae - AL450380

Mycobacterium tuberculosis H37Rv - AL123456

Mycobacterium marinum ATCC BAA-535 - CP000854. Plasmid: CP000895

Shotgun and assembly data from these projects are available from the FTP link on the right.