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Antibiotics and antimicrobial therapy
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Clinical Microbiology and Antimicrobial Chemotherapy - Official IACMAC Journal
Conferences, Seminars and Workshops

IACMAC activity plan for 2018-2019

  • Eurasian Congress on Antimicrobial Therapy and Clinical Microbiology (October 17–18, 2019, Ufa)
  • Certification workshop of professional education on specialty “Bacteriology” (October 21 – November 22, 2019, Smolensk)

Online course “Antimicrobial Stewardship: Managing Antibiotic Resistance”

You are invited to participate in Massive Open Online Course (MOOC) in Russian. This educational course was developed by Dundee University, the British Society for Antimicrobial Chemotherapy (BSAC) and the Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC).

Studies

Dear colleagues! We encourage to take part in multicenter prospective microbiological study of the antimicrobial resistance of community-acquired pathogens: S. pneumoniae, H. influenzae and S. pyogenes (PeGAS study).

Since 2015 IAC and IACMAC have conducted multicenter study aimed to evaluate the prevalence of mutation resistance to macrolide antibiotic in Mycoplasma pneumonia and Mycoplasma genitalium.

Website News

European Committee on Antimicrobial Susceptibility Testing (EUCAST) has amended the clinical classification of susceptibility (categories S,I and R): currently the clinical evaluation of susceptibility is connected with drug exposure in the nidus of infection.

The occupational standard on specialty "Medical microbiology" from the Ministry of Healthcare of the Russian Federation is posted on IACMAC website.

Clinical guidelines on diagnostics and treatment of community-acquired pneumonia in adults.

The Russian Respiratory Society (RRC) and the Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy (IACMAC) have published for discussion the clinical guidelines on diagnostics and treatment of community-acquired pneumonia in adults.

Clinical guidelines “Mucoviscidosis: microbiological diagnostics of chronic respiratory infection”

Clinical guidelines on antimicrobial susceptibility testing, approved at the IACMAC extended session in Moscow are posted on the website.

Clinical guidelines on isolation, identification and antimicrobial susceptibility of Helicobacter pylori are added.

New Articles
Site News

Is combining metronidazole and alcohol really hazardous?

It is common practice to warn against intake of alcohol (ethanol) when taking metronidazole because of the risk of an effect similar to disulfiram (Antabuse). In this article we investigate whether such a warning has any real basis.
Dec 06, 2018 - 10:15
Read more... :: Reads: 194
Site News

Antibiotic-Resistant Infections Doubled Since 2007 in Europe

More than 33,000 people died from antibiotic-resistant bacterial infections in the European Union and European Economic Area (EU/EEA) during 2015, a study has found. The estimated burden of these infections has doubled since 2007 and was similar to the combined burden of influenza, tuberculosis, and HIV.
Nov 22, 2018 - 11:10
Read more... :: Reads: 227
Site News

1 in 5 pharmacies in Spain dispenses antibiotics without prescription

Approximately one in five pharmacies in Spain dispenses antibiotics without a prescription, especially when pressured by patients, according to a recently published study.
Nov 20, 2018 - 10:15
Read more... :: Reads: 243
Site News

Single-dose versus 7-day-dose metronidazole for the treatment of trichomoniasis in women: an open-label, randomised controlled trial

Among women, trichomoniasis is the most common non-viral sexually transmitted infection worldwide, and is associated with serious reproductive morbidity, poor birth outcomes, and amplified HIV transmission. Single-dose metronidazole is the first-line treatment for trichomoniasis. However, bacterial vaginosis can alter treatment efficacy in HIV-infected women, and single-dose metronidazole treatment might not always clear infection. We compared single-dose metronidazole with a 7-day dose for the treatment of trichomoniasis among HIV-uninfected, non-pregnant women and tested whether efficacy was modified by bacterial vaginosis.
Nov 17, 2018 - 11:05
Read more... :: Reads: 216
Site News

FDA approval of Xofluza (baloxavir marboxil) for influenza

Roche announced that the US Food and Drug Administration (FDA) has approved Xofluza™ (baloxavir marboxil) for the treatment of acute, uncomplicated influenza, or flu, in people 12 years of age and older. Xofluza is a first-in-class, single-dose oral medicine with a novel proposed mechanism of action that inhibits polymerase acidic endonuclease, an enzyme essential for viral replication. Xofluza has demonstrated efficacy against a wide range of influenza viruses, including oseltamivir-resistant strains and avian strains (H7N9, H5N1) in non-clinical studies.
Nov 15, 2018 - 10:45
Read more... :: Reads: 206
Site News

Effect of Increased Daily Water Intake in Premenopausal Women With Recurrent Urinary Tract Infections: A Randomized Clinical Trial

Increased water intake is an effective antimicrobial-sparing strategy to prevent recurrent cystitis in premenopausal women at high risk for recurrence who drink low volumes of fluid daily.
Nov 13, 2018 - 10:15
Read more... :: Reads: 210
Site News

A study on the colonization of Pneumocystis jirovecii among outpatients during cancer chemotherapy and among healthy smokers

Pneumocystis Jirovecii (PJ) is regarded as an agent of fungal infection and in cases of pneumocystis pneumonia (PCP) in immune-compromised patients including cancer patients. It is not clear what kinds of cancer, treatments, and environment need prophylaxis for PCP. In this study, we have analyzed the detectability of PJ DNA from sputum, and discussed prophylaxis and risk factors regarding PCP.
Nov 10, 2018 - 09:20
Read more... :: Reads: 163
Site News

Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection

One of the most effective prophylactic strategies against periprosthetic joint infection (PJI) is administration of perioperative antibiotics. Many orthopedic surgeons are unaware of the weight-based dosing protocol for cefazolin. This study aimed at elucidating what proportion of patients receiving cefazolin prophylaxis are underdosed and whether this increases the risk of PJI.
Nov 09, 2018 - 09:40
Read more... :: Reads: 220
Site News

Four Months of Rifampin or Nine Months of Isoniazid for Latent Tuberculosis in Adults

A 9-month regimen of isoniazid can prevent active tuberculosis in persons with latent tuberculosis infection. However, the regimen has been associated with poor adherence rates and with toxic effects.
Nov 08, 2018 - 09:40
Read more... :: Reads: 159
Site News

Safety and Side Effects of Rifampin versus Isoniazid in Children

The treatment of latent infection with Mycobacterium tuberculosis is important in children because of their vulnerability to life-threatening forms of tuberculosis disease. The current standard treatment — 9 months of isoniazid — has been associated with poor adherence and toxic effects, which have hampered the effectiveness of the drug. In adults, treatment with 4 months of rifampin has been shown to be safer and to have higher completion rates than 9 months of isoniazid.
Nov 08, 2018 - 09:30
Read more... :: Reads: 136
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Institute of Antimicrobial Chemotherapy (IAC) Scientific Center of Monitoring Antimicrobial Resistance The Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy Department of Clinical Pharmacology
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